Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044196 | 0.77 | KIF11 (0.54) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL725164 | 0.74 | KIF11 (0.63) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL32668555 | 0.74 | KIF11 (0.63) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2054578 | 0.73 | KIF11 (0.46) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL25243502 | 0.72 | KIF11 (0.65) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30577796 | 0.72 | KIF11 (0.65) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30577798 | 0.72 | KIF11 (0.65) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| Methyl Alcohol SCHEMBL4018989 | 0.72 | KIF11 (0.75) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29535 | 0.72 | KIF11 (0.81) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29361452 | 0.72 | KIF11 (0.81) | KIF11GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230129371-A1 | STERICALLY HINDERED PHOSPHINO-UREA SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-04-27 | — | — | US | disclosed |
| CN-115485312-A | Sterically hindered phosphino-urea supported nickel (II) or palladium (II) catalysts for copolymerization of ethylene and polar comonomers | 陶氏环球技术有限责任公司 | 2022-12-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230129371-A1 | STERICALLY HINDERED PHOSPHINO-UREA SUPPORTED NICKEL (II) OR PALLADIUM (II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS | PCNA, NIT2, MCM7 | KIF11 3734/4885GABRA1 4470/4885GABRG2 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.