SCHEMBL725164

SCHEMBL725164

CC(C)(C)c1ccc2[nH]c3cccc(C(C)(C)C)c3c2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 10/20 0.63
GABRA1 P14867 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
GABRA2 P47869 2/20 0.40
GABRA4 P48169 2/20 0.40
GABRA6 Q16445 2/20 0.40
GHSR Q92847 1/20 0.38
HTR1D P28221 3/20 0.37
HTR1A P08908 1/20 0.35
HTR1B P28222 1/20 0.35
IMPDH2 P12268 1/20 0.35
IMPDH1 P20839 1/20 0.35
PLK4 O00444 1/20 0.35
CHEK1 O14757 1/20 0.35
AURKA O14965 1/20 0.35
CHUK O15111 1/20 0.35
PDPK1 O15530 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32668555 1.00 KIF11 (0.63) KIF11GABRA1GABRG2GABRB3GABRA5
SCHEMBL29655428 0.87 KIF11 (0.63) KIF11GABRA1GABRG2GABRB3GABRA5
SCHEMBL27844259 0.87 KIF11 (0.63) KIF11GABRA1GABRG2GABRB3GABRA5
SCHEMBL10312976 0.81 KIF11 (0.62) KIF11GABRA1GABRG2GABRB3GABRA5
SCHEMBL22044196 0.81 KIF11 (0.54) KIF11GABRA1GABRG2GABRB3GABRA5
SCHEMBL29361452 0.78 KIF11 (0.81) KIF11GABRA1GABRG2GABRB3GABRA5
SCHEMBL21765733 0.78 KIF11 (0.52) KIF11GABRA1GABRG2GABRB3GABRA5
SCHEMBL29535 0.78 KIF11 (0.81) KIF11GABRA1GABRG2GABRB3GABRA5
Dibenzofuran SCHEMBL28842309 0.78 KIF11 (0.58) KIF11GABRA1GABRG2GABRB3GABRA5
Dibenzothiophene SCHEMBL28150020 0.78 KIF11 (0.58) KIF11IMPDH2IMPDH1PLK4CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-29 US disclosed
US-9085537-B2 Photoelectric element and imaging device and driving methods therefor FUJIFILM CORPORATION (JP) 2015-07-21 US disclosed
US-9029487-B2 Process for polymerizing a polymerizable olefin and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-12 US disclosed
EP-2609123-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2013-07-03 EP disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
US-20120298846-A1 PHOTOELECTRIC ELEMENT AND IMAGING DEVICE AND DRIVING METHODS THEREFOR FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
WO-2012027448-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-01 WO disclosed
WO-2011099606-A1 PHOTOELECTRIC ELEMENT AND IMAGING DEVICE AND DRIVING METHODS THEREFOR FUJIFILM CORPORATION (JP) 2011-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device CCND1, CCND2, DRD1 KIF11 3550/4885GABRA1 2115/4885GABRG2 2780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.