⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006409 | 0.70 | — | — | |
| SCHEMBL7715753 | 0.69 | ALDH1A1 (0.37) | — | |
| SCHEMBL25906770 | 0.69 | — | — | |
| SCHEMBL14026145 | 0.67 | — | — | |
| SCHEMBL27786716 | 0.65 | HSD17B10 (0.31) | — | |
| SCHEMBL2006509 | 0.63 | HSD17B10 (0.31) | — | |
| SCHEMBL809649 | 0.63 | ALDH1A1 (0.30) | — | |
| SCHEMBL11560173 | 0.60 | HSD17B10 (0.33) | — | |
| SCHEMBL16766681 | 0.59 | ALDH1A1 (0.48) | — | |
| SCHEMBL10248853 | 0.59 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069720-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |