SCHEMBL26088955

SCHEMBL26088955

CC(C)CN1CCN(C(=O)CN2CCN(C)CC2)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MAPT P10636 2/20 0.45
POLB P06746 2/20 0.44
KDM4E B2RXH2 1/20 0.44
PKM P14618 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
MEN1 O00255 2/20 0.44
DRD2 P14416 2/20 0.44
DRD4 P21917 2/20 0.44
KMT2A Q03164 2/20 0.44
GAA P10253 1/20 0.44
ADRA1D P25100 1/20 0.44
ADRA1A P35348 1/20 0.44
ADRA1B P35368 1/20 0.44
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
BRD4 O60885 1/20 0.42
XIAP P98170 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30379642 1.00 ALDH1A1 (0.45) ALDH1A1MAPTPOLBKDM4EPKM
SCHEMBL26088477 0.90 ALDH1A1 (0.52) ALDH1A1MAPTPOLBKDM4EPKM
SCHEMBL30910082 0.90 ALDH1A1 (0.52) ALDH1A1MAPTPOLBKDM4EPKM
SCHEMBL26091403 0.89 DRD2 (0.46) ALDH1A1MAPTPOLBKDM4EMEN1
SCHEMBL30379851 0.89 DRD2 (0.46) ALDH1A1MAPTPOLBKDM4EMEN1
SCHEMBL30910045 0.88 ALDH1A1 (0.51) ALDH1A1MAPTPOLBKDM4EPKM
SCHEMBL26091906 0.88 ALDH1A1 (0.51) ALDH1A1MAPTPOLBKDM4EPKM
SCHEMBL30379884 0.84 BRD4 (0.64) ALDH1A1POLBKDM4EPKMMEN1
SCHEMBL26088857 0.84 BRD4 (0.64) ALDH1A1POLBKDM4EPKMMEN1
SCHEMBL30379814 0.83 ALDH1A1 (0.45) ALDH1A1MAPTPOLBKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023068755-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 사피엔스바이오 2023-04-27 WO claimed
CN-118119612-A Novel compounds and pharmaceutical compositions comprising the same 萨皮恩斯生物有限公司 2024-05-31 CN disclosed
WO-2023068755-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 사피엔스바이오 2023-04-27 WO disclosed