Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31313650 | 1.00 | PRMT1 (0.54) | PRMT1MAPK1LMNADRD2DRD4 | |
| SCHEMBL27042396 | 0.90 | KDM4E (0.47) | PRMT1MAPK1LMNATSHRALDH1A1 | |
| SCHEMBL27042601 | 0.88 | DRD4 (0.50) | LMNADRD2DRD4SCN4A | |
| SCHEMBL26092030 | 0.82 | FDFT1 (0.46) | MAPK1ALDH1A1KDM4E | |
| SCHEMBL26093038 | 0.82 | FDFT1 (0.46) | MAPK1ALDH1A1KDM4E | |
| SCHEMBL27042490 | 0.81 | PRMT1 (0.50) | PRMT1MAPK1LMNATSHRALDH1A1 | |
| SCHEMBL30728773 | 0.81 | PRMT1 (0.50) | PRMT1MAPK1LMNATSHRALDH1A1 | |
| SCHEMBL30728803 | 0.81 | PRMT1 (0.50) | PRMT1MAPK1LMNATSHRALDH1A1 | |
| SCHEMBL31533977 | 0.80 | TSHR (0.50) | PRMT1DRD2DRD4TSHRALDH1A1 | |
| SCHEMBL30728753 | 0.80 | PRMT1 (0.49) | PRMT1MAPK1LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558489-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-05-28 | — | — | EP | disclosed |
| EP-4419516-A1 | PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-08-28 | — | — | EP | disclosed |
| CN-118284601-A | Pyrrolidine derivatives as DDR inhibitors | 奇斯药制品公司 | 2024-07-02 | — | — | CN | disclosed |
| WO-2024017876-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | disclosed |
| WO-2024017876-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023066834-A1 | PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023066834-A1 | PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-04-27 | — | — | WO | disclosed |