Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26092030 | 1.00 | FDFT1 (0.46) | FDFT1ALDH1A1MAPK1DRD3TDP1 | |
| SCHEMBL26428969 | 0.86 | NPSR1 (0.47) | FDFT1ALDH1A1TDP1POLBKDM4E | |
| SCHEMBL26428976 | 0.86 | NPSR1 (0.47) | FDFT1ALDH1A1TDP1POLBKDM4E | |
| SCHEMBL31015904 | 0.86 | NPSR1 (0.47) | FDFT1ALDH1A1TDP1POLBKDM4E | |
| SCHEMBL26092608 | 0.86 | NPSR1 (0.47) | FDFT1ALDH1A1TDP1POLBKDM4E | |
| SCHEMBL30349607 | 0.86 | NPSR1 (0.47) | FDFT1ALDH1A1TDP1POLBKDM4E | |
| SCHEMBL31015900 | 0.86 | NPSR1 (0.47) | FDFT1ALDH1A1TDP1POLBKDM4E | |
| SCHEMBL3040729 | 0.83 | FDFT1 (0.53) | FDFT1ALDH1A1TDP1POLBRAB9A | |
| SCHEMBL31313650 | 0.82 | PRMT1 (0.54) | ALDH1A1MAPK1KDM4E | |
| SCHEMBL26089322 | 0.82 | PRMT1 (0.54) | ALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017876-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023066834-A1 | PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-04-27 | — | — | WO | disclosed |