Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.81 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.48 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lacmoid SCHEMBL29455251 | 1.00 | SNCA (0.81) | SNCAAPPBACE1TYRPTPN1 | |
| SCHEMBL13521269 | 0.93 | SNCA (0.71) | SNCAAPPBACE1TYRPTPN1 | |
| SCHEMBL2609269 | 0.90 | SNCA (1.00) | SNCAAPPBACE1TYRPTPN1 | |
| SCHEMBL13556902 | 0.84 | SNCA (0.87) | SNCAAPPBACE1TYRPTPN1 | |
| SCHEMBL13083868 | 0.78 | SNCA (0.54) | SNCAAPPPTPN1KMT2AHPGD | |
| SCHEMBL3776968 | 0.72 | ALDH1A1 (0.68) | SNCAAPPBACE1TYRPTPN1 | |
| SCHEMBL29052306 | 0.72 | MAPT (0.68) | SNCAAPPKMT2AHPGDMEN1 | |
| SCHEMBL327849 | 0.72 | APP (0.63) | SNCAAPPBACE1TYRPTPN1 | |
| SCHEMBL12714456 | 0.70 | SNCA (0.47) | SNCAAPPKMT2AHPGDMEN1 | |
| SCHEMBL12714421 | 0.70 | SNCA (0.47) | SNCAAPPKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210302442-A1 | A FRET-BASED METHOD TO MEASURE SEEDING ACTIVITY OF MISFOLDED PROTEIN SPECIES IN BIOLOGICAL SAMPLES | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (DE) | 2021-09-30 | — | — | US | disclosed |
| US-8559093-B2 | Electrochromic mirror reflective element for vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2013-10-15 | — | — | US | disclosed |
| US-8559093-B2 | Electrochromic mirror reflective element for vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2013-10-15 | — | — | US | disclosed |
| US-20130063802-A1 | VARIABLE TRANSMISSION WINDOW | DONNELLY CORPORATION (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130063802-A1 | VARIABLE TRANSMISSION WINDOW | DONNELLY CORPORATION (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2012136655-A1 | PHENOXAZINONES OR PHENOTHIAZONES AS INHIBITORS OF AMYLOID FORMATION | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2012-10-11 | — | — | WO | disclosed |
| EP-2508186-A1 | Phenoxazinones or phenothiazones as inhibitors of amyloid formation | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2012-10-10 | — | — | EP | disclosed |
| EP-2508186-A1 | Phenoxazinones or phenothiazones as inhibitors of amyloid formation | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2012-10-10 | — | — | EP | disclosed |
| US-20120206790-A1 | ELECTROCHROMIC MIRROR REFLECTIVE ELEMENT FOR VEHICULAR REARVIEW MIRROR ASSEMBLY | DONNELLY CORPORATION (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120206790-A1 | ELECTROCHROMIC MIRROR REFLECTIVE ELEMENT FOR VEHICULAR REARVIEW MIRROR ASSEMBLY | DONNELLY CORPORATION (US) | 2012-08-16 | — | — | US | disclosed |
| US-7589883-B2 | Vehicular exterior mirror | DONNELLY CORPORATION (US) | 2009-09-15 | — | — | US | disclosed |
| US-7589883-B2 | Vehicular exterior mirror | DONNELLY CORPORATION (US) | 2009-09-15 | — | — | US | disclosed |
| US-20080094685-A1 | VEHICULAR EXTERIOR MIRROR | DONNELLY CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080094685-A1 | VEHICULAR EXTERIOR MIRROR | DONNELLY CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
| US-7349144-B2 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2008-03-25 | — | — | US | disclosed |
| US-7349144-B2 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2008-03-25 | — | — | US | disclosed |
| US-20070184284-A1 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2007-08-09 | — | — | US | disclosed |
| US-20070184284-A1 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2007-08-09 | — | — | US | disclosed |
| US-7202987-B2 | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices | DONNELLY CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202987-B2 | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices | DONNELLY CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210302442-A1 | A FRET-BASED METHOD TO MEASURE SEEDING ACTIVITY OF MISFOLDED PROTEIN SPECIES IN BIOLOGICAL SAMPLES | HTT, APBA1, HSPBP1 | SNCA 101/4885APP 7/4885BACE1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.