Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.52 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 14/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30374587 | 1.00 | CRHR1 (0.52) | CRHR1PDE2APDE10ASCN9ASPR | |
| SCHEMBL30295410 | 0.88 | CRHR1 (0.46) | CRHR1SCN9ASPRLRRK2ALOX5AP | |
| SCHEMBL26092744 | 0.88 | CRHR1 (0.46) | CRHR1SCN9ASPRLRRK2ALOX5AP | |
| SCHEMBL30295416 | 0.84 | CRHR1 (0.58) | CRHR1SCN9ASPRLRRK2ALOX5AP | |
| SCHEMBL30295310 | 0.84 | CRHR1 (0.43) | CRHR1PDE2ASCN9ASPRLRRK2 | |
| SCHEMBL26439328 | 0.82 | NLRP3 (0.53) | PDE2APDE10AALOX5APFEN1 | |
| SCHEMBL26439270 | 0.82 | CRHR1 (0.41) | CRHR1PDE2APDE10ASCN9AALOX5AP | |
| SCHEMBL30295421 | 0.82 | HSP90AA1 (0.49) | CRHR1PDE2APDE10ASCN9A | |
| SCHEMBL26439827 | 0.82 | HSP90AA1 (0.49) | CRHR1PDE2APDE10ASCN9A | |
| SCHEMBL31309237 | 0.80 | CRHR1 (0.45) | CRHR1SCN9ASPRLRRK2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735433-A2 | SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF | Viva Star Biosciences (US) Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006681-A2 | SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF | VIVA STAR BIOSCIENCES (US) INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| CN-116102535-A | Nitrogen-containing compound, preparation method and application thereof | 索智生物科技（浙江）有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |