Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26091356 | 0.95 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL3L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL26090581 | 0.79 | HRH3 (0.39) | L3MBTL3L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL26093792 | 0.79 | HRH3 (0.36) | KDM4EALDH1A1LMNAHRH3MEN1 | |
| SCHEMBL1306587 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL3L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL644944 | 0.76 | RECQL (0.48) | SMN1; SMN2L3MBTL1ALDH1A1RECQLHPGD | |
| SCHEMBL14582189 | 0.76 | RECQL (0.48) | SMN1; SMN2L3MBTL1ALDH1A1RECQLHPGD | |
| Hydrochloric Acid SCHEMBL31693240 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL3L3MBTL1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31693414 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL3L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2791591 | 0.74 | RECQL (0.47) | SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL19775351 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL3L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066190-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-04-27 | — | — | WO | claimed |