Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14582189 | 1.00 | RECQL (0.48) | RECQLALDH1A1GAANPC1RAB9A | |
| SCHEMBL2791591 | 0.98 | RECQL (0.47) | RECQLALDH1A1GAANPC1RAB9A | |
| SCHEMBL8532924 | 0.91 | RECQL (0.46) | RECQLALDH1A1GAANPC1RAB9A | |
| SCHEMBL8530047 | 0.91 | RECQL (0.46) | RECQLALDH1A1GAANPC1RAB9A | |
| SCHEMBL8532927 | 0.91 | RECQL (0.46) | RECQLALDH1A1GAANPC1RAB9A | |
| SCHEMBL8530051 | 0.91 | RECQL (0.46) | RECQLALDH1A1GAANPC1RAB9A | |
| SCHEMBL27586626 | 0.86 | — | — | |
| SCHEMBL26091356 | 0.80 | SMN1; SMN2 (0.40) | RECQLALDH1A1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL644462 | 0.78 | — | — | |
| SCHEMBL26094010 | 0.76 | SMN1; SMN2 (0.40) | RECQLALDH1A1SMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018145921-A1 | COMPOSITION FOR CONTROLLING HARMFUL MICROORGANISMS COMPRISING 1 -(PHENOXY-PYRIDINYL)-2-(1,2,4-TRIAZOL-1 -YL)-ETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-16 | — | — | WO | claimed |
| WO-2018050535-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | claimed |
| EP-2651209-A2 | SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF | Syngenta Participations AG (CH) | 2013-10-23 | — | — | EP | claimed |
| WO-2012082548-A2 | SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-21 | — | — | WO | claimed |
| US-8120854-B2 | Substituted acrylamide polymer disposed between reflective layers; bonding strength; document counterfeiting prevention | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-02-21 | — | — | US | claimed |
| WO-2010084182-A1 | METHODS FOR MAKING VALERENIC ACID DERIVATIVES AND THEIR USE | Universität Wien (AT) | 2010-07-29 | — | — | WO | claimed |
| EP-2126616-A1 | INTERFERENCE FILMS HAVING ACRYLAMIDE LAYER AND METHOD OF MAKING SAME | 3M Innovative Properties Company (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008082935-A1 | INTERFERENCE FILMS HAVING ACRYLAMIDE LAYER AND METHOD OF MAKING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-07-10 | — | — | WO | claimed |
| US-20080160185-A1 | INTERFERENCE FILMS HAVING ACRYLAMIDE LAYER AND METHOD OF MAKING SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2008-07-03 | — | — | US | claimed |
| EP-4384016-A1 | ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE | Bayer Aktiengesellschaft (DE) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023066190-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023017120-A1 | ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE | BAYER AKTIENGESELLSCHAFT (DE) | 2023-02-16 | — | — | WO | disclosed |
| WO-2021068179-A1 | NOVEL HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-04-15 | — | — | WO | disclosed |
| CN-105198800-A | Preparation method of pesticide intermediate, namely 2,3-dichloro-5-methylpyridine | JIANGSU YANGNONG CHEMICAL GROUP CO LTD | 2015-12-30 | — | — | CN | disclosed |
| EP-1716133-B1 | 2-(PIPERIDIN-4-YL)-4,5-DIHYDRO-2H-PYRIDAZIN-3-ONE DERIVATIVES AS PDE4 INHIBITORS | NYCOMED GMBH (DE) | 2008-03-26 | — | — | EP | disclosed |
| US-20070179146-A1 | 2-(Piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors | ATLANTA PHARMA AG (DE) | 2007-08-02 | — | — | US | disclosed |
| EP-1716133-A1 | 2-(PIPERIDIN-4-YL)-4,5-DIHYDRO-2H-PYRIDAZIN-3-ONE DERIVATIVES AS PDE4 INHIBITORS | Altana Pharma AG (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005075456-A1 | 2-(PIPERIDIN-4-YL) -4, 5-DIHYDRO-2H-PYRIDAZIN-3-ONE DERIVATIVES AS PDE4 INHIBITORS | ALTANA PHARMA AG (DE) | 2005-08-18 | — | — | WO | disclosed |
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179146-A1 | 2-(Piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors | PDE4A, PDE4B, PDE4D | RECQL 585/4885ALDH1A1 338/4885GAA 1083/4885 |
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | RECQL 3481/4885ALDH1A1 1071/4885GAA 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.