SCHEMBL26095196

SCHEMBL26095196

c1cc(N=Nc2ccc(Oc3ccc(N=Nc4cc[nH]n4)cc3)cc2)n[nH]1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
GAA P10253 2/20 0.38
RAB9A P51151 2/20 0.38
GFER P55789 1/20 0.38
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
LMNA P02545 3/20 0.33
MAPK1 P28482 3/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
PTGS2 P35354 1/20 0.33
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GSK3B P49841 2/20 0.31
ELANE P08246 1/20 0.31
FURIN P09958 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5206443 0.81
Azobenzene SCHEMBL11590710 0.80 ALDH1A1 (0.50) MAPTGAARAB9AGFERADRA2B
SCHEMBL2554754 0.80 ALDH1A1 (0.50) MAPTGAARAB9AGFERADRA2B
SCHEMBL27330089 0.78 ALDH1A1 (0.48) MAPTGAARAB9AGFERADRA2B
SCHEMBL26095460 0.77
Naphthalene SCHEMBL11589769 0.71 CYP2A6 (0.36) MAPTRAB9AMAPK1NPC1HAO1
SCHEMBL6756759 0.70 MAOA (0.40) MAPTGAARAB9AGFERLMNA
SCHEMBL6269293 0.69
SCHEMBL15349277 0.69
SCHEMBL29088729 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4174079-B1 CISPLATIN DERIVATIVE WITH UV / VIS LIGHT-CONTROLLED CYTOTOXICITY , METHOD OF PRODUCING THEREOF AND ITS USE IN ANTI-CANCER THERAPY UNIV JAGIELLONSKI (PL) 2024-04-24 EP disclosed
EP-4174079-A1 CISPLATIN DERIVATIVE WITH CYTOTOXICITY CONTROLLED BY UV / VIS LIGHT, METHOD OF ITS PRODUCTION AND USE IN ANTI-CANCER THERAPY UNIWERSYTET JAGIELLONSKI (PL) 2023-05-03 EP disclosed