SCHEMBL26096048

SCHEMBL26096048

O=C(Nc1ccc(-c2cc(-c3cccc(OC(F)(F)F)c3)[nH]n2)cc1)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
TP53 P04637 2/20 0.45
HDAC6 Q9UBN7 1/20 0.45
RAF1 P04049 3/20 0.45
ABL1 P00519 3/20 0.44
BRAF P15056 1/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TNIK Q9UKE5 1/20 0.42
LRRK2 Q5S007 1/20 0.42
FLT3 P36888 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
DHFR P00374 1/20 0.41
EPHB4 P54760 1/20 0.41
TEK Q02763 1/20 0.41
KDR P35968 1/20 0.41
JAK2 O60674 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26477359 0.96 RAF1 (0.49) MAPTTP53HDAC6RAF1ABL1
SCHEMBL26094970 0.89 MAPT (0.53) MAPTTP53HDAC6RAF1BRAF
SCHEMBL26464921 0.84 MAPT (0.55) MAPTTP53HDAC6RAF1ABL1
SCHEMBL26466956 0.76 RAF1 (0.48) MAPTRAF1BRAFSMN1; SMN2BCHE
SCHEMBL26477355 0.76 XDH (0.51) MAPTRAF1ABL1NPC1RAB9A
SCHEMBL26477853 0.76 XDH (0.51) MAPTABL1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL31660319 0.76 RAF1 (0.47) MAPTRAF1BRAFSMN1; SMN2BCHE
SCHEMBL26467065 0.75 RAF1 (0.51) MAPTTP53RAF1BRAFSMN1; SMN2
SCHEMBL31660378 0.75 RAF1 (0.51) MAPTTP53RAF1BRAFSMN1; SMN2
SCHEMBL26467185 0.74 MAPT (0.48) MAPTTP53NPC1RAB9ANTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP claimed
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-07-17 US disclosed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP disclosed
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL APP, APBA1, PRNP MAPT 8/4885TP53 2542/4885HDAC6 2055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.