Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 3/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26096048 | 0.96 | MAPT (0.45) | RAF1BRAFMAPTTP53ABL1 | |
| SCHEMBL26464921 | 0.89 | MAPT (0.55) | RAF1BRAFMAPTTP53ABL1 | |
| SCHEMBL26094970 | 0.84 | MAPT (0.53) | RAF1BRAFMAPTTP53HDAC6 | |
| SCHEMBL26477355 | 0.80 | XDH (0.51) | RAF1MAPTABL1PRKD1NPC1 | |
| SCHEMBL26466956 | 0.76 | RAF1 (0.48) | RAF1BRAFMAPTBCHEACHE | |
| SCHEMBL26477853 | 0.76 | XDH (0.51) | MAPTABL1SMN1; SMN2RAB9AXDH | |
| Hydrochloric Acid SCHEMBL31660319 | 0.76 | RAF1 (0.47) | RAF1BRAFMAPTBCHEACHE | |
| SCHEMBL31660378 | 0.75 | RAF1 (0.51) | RAF1BRAFMAPTTP53BCHE | |
| SCHEMBL26467065 | 0.75 | RAF1 (0.51) | RAF1BRAFMAPTTP53BCHE | |
| SCHEMBL26478317 | 0.74 | MAPT (0.51) | MAPTTP53PRKD1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |