Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5290702 | 0.98 | MAPT (0.38) | MAPTNPSR1GAAALDH1A1RECQL | |
| SCHEMBL1830962 | 0.81 | RECQL (0.44) | MAPTNPSR1GAAALDH1A1RECQL | |
| SCHEMBL23225702 | 0.77 | SLC6A2 (0.36) | NPSR1GAAALDH1A1RECQLPOLB | |
| SCHEMBL26704216 | 0.77 | MAOA (0.36) | NPSR1GAAALDH1A1KDM4ETSHR | |
| SCHEMBL27951184 | 0.76 | AKT1 (0.39) | — | |
| SCHEMBL5287089 | 0.75 | DRD2 (0.39) | MAPTNPSR1GAARECQLSMN1; SMN2 | |
| SCHEMBL5282609 | 0.74 | NPSR1 (0.35) | MAPTNPSR1GAAALDH1A1RECQL | |
| SCHEMBL5333137 | 0.74 | MAPT (0.38) | MAPTNPSR1GAAALDH1A1RECQL | |
| SCHEMBL18250336 | 0.74 | MAOA (0.36) | MAPTGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1834758 | 0.74 | MAOA (0.36) | MAPTGAAALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137820-A1 | PHOSPHORESCENT aNHC-BASED PLATINUM (II) COMPLEXES | Technische Universität Dresden (DE) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137820-A1 | PHOSPHORESCENT aNHC-BASED PLATINUM (II) COMPLEXES | NDC1, ORC3, NUDC | MAPT 955/4885NPSR1 879/4885GAA 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.