SCHEMBL2609782

SCHEMBL2609782

CCC(O)COC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.56
TSHR P16473 3/20 0.38
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14901101 1.00 MAPK1 (0.56) MAPK1TSHRKDM4EALDH1A1TDP1
SCHEMBL14901102 1.00 MAPK1 (0.56) MAPK1TSHRKDM4EALDH1A1TDP1
SCHEMBL20089291 0.91 MAPK1 (0.48) MAPK1TSHRKDM4EALDH1A1TDP1
SCHEMBL1982314 0.86 MAPK1 (0.65) MAPK1TSHRKDM4EALDH1A1TDP1
SCHEMBL6669573 0.83 MAPK1 (0.45) MAPK1TSHR
SCHEMBL18027553 0.82 MAPK1 (0.54) MAPK1KDM4EALDH1A1TDP1
SCHEMBL1927186 0.82 MAPK1 (0.54) MAPK1KDM4EALDH1A1TDP1
SCHEMBL18027532 0.82 MAPK1 (0.54) MAPK1KDM4EALDH1A1TDP1
SCHEMBL1927183 0.82 MAPK1 (0.54) MAPK1KDM4EALDH1A1TDP1
SCHEMBL14649738 0.82 MAPK1 (0.37) MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111575068-B Gasoline containing gasoline octane number promoter 深圳飞扬骏研新材料股份有限公司 2022-08-05 CN claimed
CN-110240950-A Methanol gasoline additive, preparation method and the methanol gasoline containing the additive 深圳市前海博扬研究院有限公司 2019-09-17 CN claimed
US-5674827-A A THREE COMPONENT AQUEOUS MIXTURE COMPRISING 1,2-BUTANEDIOL, A WATER SOLUBLE ACYCLIC ETHER ALCOHOL, I.E., 1-TERT-BUTOXY-2-BUTANOL AND 4-METHYL-4-HYDROXY-2-PENTANONE; MATERIALS HANDLING; POLLUTION CONTROL MITSUBISHI CHEMICAL CORPORATION (JP) 1997-10-07 US claimed
CN-1108687-A Degreasing detergent and method for cleaning oil deposit MITSUBISHI CHEM CORP (JP) 1995-09-20 CN claimed
EP-0662529-A1 Degreasing cleaner and method for cleaning oil-deposited material Mitsubishi Chemical Corporation (JP) 1995-07-12 EP claimed
JP-10101606-A None JP disclosed
US-20230364086-A1 COMBINATION THERAPIES WITH EHMT2 INHIBITORS Epizyme, Inc. 2023-11-16 US disclosed
US-11672800-B2 Combination therapies with EHMT2 inhibitors Epizyme, Inc. (US) 2023-06-13 US disclosed
CN-111575068-B Gasoline containing gasoline octane number promoter 深圳飞扬骏研新材料股份有限公司 2022-08-05 CN disclosed
EP-3900794-A2 METHOD OF USING IN SITU COMPLEXATION OF SURFACTANTS FOR FOAM CONTROL AND CONDITIONING JOHNSON & JOHNSON CONSUMER INC. (US) 2021-10-27 EP disclosed
CN-111575068-A Gasoline octane number promoter 深圳市前海博扬研究院有限公司 2020-08-25 CN disclosed
EP-2981557-B1 GLYCOGEN-BASED WATER SOLUBILITY ENHANCERS ACRAF (IT) 2020-02-05 EP disclosed
JP-H10101606-A PRODUCTION OF 1,2-BUTANEDIOL MONO-TERTIARY-BUTYL ETHER MITSUBISHI CHEM CORP 1998-04-21 JP disclosed
EP-0662529-B1 Degreasing cleaner and method for cleaning oil-deposited material MITSUBISHI CHEM CORP (JP) 1997-10-15 EP disclosed
US-5674827-A A THREE COMPONENT AQUEOUS MIXTURE COMPRISING 1,2-BUTANEDIOL, A WATER SOLUBLE ACYCLIC ETHER ALCOHOL, I.E., 1-TERT-BUTOXY-2-BUTANOL AND 4-METHYL-4-HYDROXY-2-PENTANONE; MATERIALS HANDLING; POLLUTION CONTROL MITSUBISHI CHEMICAL CORPORATION (JP) 1997-10-07 US disclosed
CN-1108687-A Degreasing detergent and method for cleaning oil deposit MITSUBISHI CHEM CORP (JP) 1995-09-20 CN disclosed
EP-0662529-A1 Degreasing cleaner and method for cleaning oil-deposited material Mitsubishi Chemical Corporation (JP) 1995-07-12 EP disclosed
EP-0594621-A1 PROCESS FOR ENZYMATICALLY PREPARING ENANTIOMER-FREE ESTERS AND ALCOHOLS Roche Diagnostics GmbH (DE) 1994-05-04 EP disclosed
WO-1993002034-A1 PROCESS FOR ENZYMATICALLY PREPARING ENANTIOMER-FREE ESTERS AND ALCOHOLS BOEHRINGER MANNHEIM GMBH (DE) 1993-02-04 WO disclosed
WO-1991009823-A1 PHOTOCATALYTIC PROCESS FOR DEGRADATION OF ORGANIC MATERIALS IN A VAPORIZED OR GASEOUS STATE TRUSTEES OF BOSTON UNIVERSITY (US) 1991-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230364086-A1 COMBINATION THERAPIES WITH EHMT2 INHIBITORS EHMT2, BHMT, SHMT2 MAPK1 3668/4885TSHR 2922/4885KDM4E 502/4885
US-11672800-B2 Combination therapies with EHMT2 inhibitors EHMT2, BHMT, SHMT2 MAPK1 3668/4885TSHR 2922/4885KDM4E 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.