SCHEMBL2609855

SCHEMBL2609855

CC1(C)c2ccccc2-c2ccc(N(c3ccccc3)c3ccc(-c4ccc5c(c4)C(C)(C)c4cc6c7ccccc7n(-c7ccccc7)c6cc4-5)cc3)cc21

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PDK2 Q15119 2/20 0.31
TSPO P30536 1/20 0.30
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609861 0.99 KDM4E (0.36) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL2609856 0.98 KDM4E (0.35) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL21369335 0.94 KDM4E (0.34) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL31750 0.94 KDM4E (0.34) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL15752527 0.93 TSPO (0.31) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL12196237 0.93 KDM4E (0.36) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL12196614 0.93 KDM4E (0.36) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL31871 0.93 KDM4E (0.36) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL9916438 0.93 KDM4E (0.38) KDM4EATML3MBTL1PDK2HDAC4
SCHEMBL19444835 0.93 KDM4E (0.38) KDM4EATML3MBTL1PDK2HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9224961-B2 Condensed-cyclic compound, organic light-emitting diode comprising the same and flat panel display device comprising the organic light-emitting diode SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-29 US disclosed
US-9224961-B2 Condensed-cyclic compound, organic light-emitting diode comprising the same and flat panel display device comprising the organic light-emitting diode SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-29 US disclosed
US-20120097932-A1 CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 US disclosed
US-20120097932-A1 CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120097932-A1 CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE OCIAD1, OCIAD2, CFD KDM4E 3315/4885ATM 4310/4885L3MBTL1 2477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.