Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | LDLR | P01130 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23675404 | 0.86 | NPC1 (0.64) | CDK1ALDH1A1GAAHPGDSENP1 | |
| SCHEMBL23675423 | 0.79 | NPC1 (0.63) | ALDH1A1GAAHPGDSENP1P2RX1 | |
| SCHEMBL26096785 | 0.79 | NPC1 (0.63) | ALDH1A1GAAHPGDSENP1P2RX1 | |
| SCHEMBL23675401 | 0.77 | NPC1 (0.60) | CDK1ALDH1A1GAAHPGDSENP1 | |
| SCHEMBL8980687 | 0.77 | CDK1 (0.82) | CDK1ALDH1A1HPGDTDP1P2RX1 | |
| SCHEMBL3455872 | 0.77 | RAB9A (0.55) | HPGDCHRM1TDP1NPC1RAB9A | |
| Ethylenediamine SCHEMBL1543210 | 0.75 | CDK1 (0.68) | CDK1TDP1P2RX1TMPRSS4PTGS1 | |
| SCHEMBL1114775 | 0.75 | CDK1 (0.68) | CDK1HPGDCHRM1TDP1P2RX1 | |
| SCHEMBL4748888 | 0.74 | ALDH1A1 (0.62) | CDK1ALDH1A1GAAHPGDSENP1 | |
| SCHEMBL26098051 | 0.74 | CNR2 (0.53) | CDK1CHRM1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIV OF TEXAS SY (US) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | EIF2AK2, SARS1, ACE | CDK1 3435/4885ALDH1A1 770/4885GAA 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.