SCHEMBL2609865

SCHEMBL2609865

CC1(C)c2cc(-c3ccc4ccc5cccc6ccc3c4c56)ccc2-c2ccc3c4ccccc4n(-c4ccccc4)c3c21

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ERBB2 P04626 1/20 0.32
CYP1A2 P05177 1/20 0.32
FYN P06241 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 1/20 0.32
AHR P35869 1/20 0.32
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25741169 0.89 KDM4E (0.33) KDM4EATML3MBTL1RXFP1
SCHEMBL2609886 0.88 L3MBTL1 (0.41) KDM4EATML3MBTL1RXFP1
SCHEMBL2609891 0.87 L3MBTL1 (0.41) KDM4EATML3MBTL1RXFP1
SCHEMBL14685282 0.86 L3MBTL1 (0.40) KDM4EATML3MBTL1RXFP1
SCHEMBL2609872 0.86 KDM4E (0.37) KDM4EATML3MBTL1ERBB2CYP1A2
SCHEMBL2609880 0.85 KDM4E (0.42) KDM4EATML3MBTL1
SCHEMBL2609887 0.85 KDM4E (0.39) KDM4EATML3MBTL1
SCHEMBL2609888 0.85 L3MBTL1 (0.39) KDM4EATML3MBTL1RXFP1
SCHEMBL2609901 0.85 KDM4E (0.39) KDM4EATML3MBTL1
SCHEMBL25741166 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9224961-B2 Condensed-cyclic compound, organic light-emitting diode comprising the same and flat panel display device comprising the organic light-emitting diode SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-29 US disclosed
US-9224961-B2 Condensed-cyclic compound, organic light-emitting diode comprising the same and flat panel display device comprising the organic light-emitting diode SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-29 US disclosed
US-20120097932-A1 CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 US disclosed
US-20120097932-A1 CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120097932-A1 CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE OCIAD1, OCIAD2, CFD KDM4E 3315/4885ATM 4310/4885L3MBTL1 2477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.