SCHEMBL26098994 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	EGFR	P00533	5/20	0.44

▸	ERBB2	P04626	1/20	0.43

▸	KIT	P10721	3/20	0.43

▸	MAPK7	Q13164	1/20	0.43

▸	BRAF	P15056	4/20	0.42

▸	KRAS	P01116	1/20	0.40

▸	SOS1	Q07889	1/20	0.40

▸	KDR	P35968	2/20	0.39

▸	IRAK4	Q9NWZ3	1/20	0.38

▸	RAF1	P04049	1/20	0.36

▸	PDE10A	Q9Y233	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26100926	0.95	EGFR (0.47)	EGFRERBB2KITMAPK7BRAF
SCHEMBL26101576	0.94	EGFR (0.45)	EGFRERBB2KITMAPK7BRAF
SCHEMBL26135306	0.94	EGFR (0.45)	EGFRERBB2KITMAPK7BRAF
SCHEMBL26102740	0.87	EGFR (0.45)	EGFRERBB2KITMAPK7BRAF
SCHEMBL26101745	0.86	SOS1 (0.45)	EGFRERBB2MAPK7KRASSOS1
SCHEMBL26099799	0.86	KDR (0.46)	EGFRKITMAPK7KDRIRAK4
SCHEMBL26100035	0.86	KDR (0.46)	EGFRKITMAPK7KDRIRAK4
SCHEMBL26102185	0.85	KIT (0.46)	EGFRKITMAPK7KDRIRAK4
SCHEMBL26099351	0.85	KIT (0.46)	EGFRKITMAPK7KDRIRAK4
SCHEMBL30393198	0.85	EGFR (0.50)	EGFRERBB2KITMAPK7PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023075529-A1	QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF	보로노이바이오 주식회사	2023-05-04	—	—	WO	claimed
WO-2023075529-A1	QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF	보로노이바이오 주식회사	2023-05-04	—	—	WO	disclosed