Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.44 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102185 | 1.00 | KIT (0.46) | KITIRAK4MAPK7ENPP1PDPK1 | |
| SCHEMBL26100035 | 0.91 | KDR (0.46) | KITIRAK4MAPK7ENPP1SLC2A1 | |
| SCHEMBL26099799 | 0.91 | KDR (0.46) | KITIRAK4MAPK7ENPP1SLC2A1 | |
| SCHEMBL30394062 | 0.86 | EGFR (0.49) | KITIRAK4MAPK7RPS6KB1SLC2A1 | |
| SCHEMBL26101933 | 0.86 | EGFR (0.49) | KITIRAK4MAPK7RPS6KB1SLC2A1 | |
| SCHEMBL26101193 | 0.86 | MAPK7 (0.43) | KITMAPK7SLC2A1CTSSKDR | |
| SCHEMBL26101421 | 0.86 | MAPK7 (0.43) | KITMAPK7SLC2A1CTSSKDR | |
| SCHEMBL26098994 | 0.85 | EGFR (0.44) | KITIRAK4MAPK7KDREGFR | |
| SCHEMBL26099840 | 0.85 | EGFR (0.43) | KITIRAK4ENPP1KDREGFR | |
| SCHEMBL30891778 | 0.85 | MAPK7 (0.45) | KITIRAK4MAPK7ENPP1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |