Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | KIT | P10721 | 7/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL26099390 | 0.84 | ABCG2 (0.49) | ABCG2KITACHEBACE1PDGFRB | |
| SCHEMBL30393169 | 0.81 | ABCG2 (0.57) | ABCG2KITACHEBACE1PDGFRB | |
| SCHEMBL26101189 | 0.80 | PDGFRB (0.50) | KITPDGFRBPDGFRAKDRPDE10A | |
| SCHEMBL26102054 | 0.78 | ABCG2 (0.54) | ABCG2KITACHEBACE1PDGFRB | |
| SCHEMBL26101213 | 0.78 | ABCG2 (0.53) | ABCG2KITACHEBACE1PDGFRB | |
| SCHEMBL31137830 | 0.72 | PDGFRB (0.48) | ABCG2KITACHEBACE1PDGFRB | |
| SCHEMBL30394041 | 0.72 | MAPT (0.55) | ABCG2ACHEBACE1PDGFRBPDGFRA | |
| Hydrochloric Acid SCHEMBL30891771 | 0.72 | KDR (0.51) | ABCG2KITACHEBACE1PDGFRB | |
| SCHEMBL30394491 | 0.72 | EGFR (0.57) | ABCG2KITACHEBACE1PDGFRB | |
| SCHEMBL26100068 | 0.72 | EGFR (0.57) | ABCG2KITACHEBACE1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |