Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 10/20 | 0.46 |
| ▸ | KDR | P35968 | 6/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.43 |
| ▸ | FLT4 | P35916 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | KIF5B | P33176 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | CIT | O14578 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 1/20 | 0.42 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | STK10 | O94804 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101805 | 0.91 | KIT (0.46) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26100098 | 0.91 | EGFR (0.56) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26100864 | 0.89 | KIT (0.44) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26103031 | 0.89 | KIT (0.46) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26103035 | 0.88 | KIT (0.46) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26102144 | 0.87 | EGFR (0.46) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26099034 | 0.87 | KIT (0.45) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26099433 | 0.85 | EGFR (0.52) | KITEGFRKDRPDGFRBFLT3 | |
| SCHEMBL30394281 | 0.85 | EGFR (0.52) | KITEGFRKDRPDGFRBFLT3 | |
| SCHEMBL26098297 | 0.85 | EGFR (0.51) | KITEGFRKDRFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |