Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 10/20 | 0.44 |
| ▸ | KDR | P35968 | 5/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | FLT4 | P35916 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KIF5B | P33176 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099430 | 0.89 | KIT (0.48) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26103035 | 0.84 | KIT (0.46) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26103279 | 0.83 | EGFR (0.53) | KITEGFRKDRFLT4RET | |
| SCHEMBL26099034 | 0.82 | KIT (0.45) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26103031 | 0.82 | KIT (0.46) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26099433 | 0.81 | EGFR (0.52) | KITEGFRKDRPDGFRB | |
| SCHEMBL30394281 | 0.81 | EGFR (0.52) | KITEGFRKDRPDGFRB | |
| SCHEMBL30891766 | 0.81 | KDR (0.51) | KITEGFRKDRFGFR1FLT1 | |
| SCHEMBL26103039 | 0.81 | EGFR (0.50) | KITEGFRKDRPDGFRB | |
| SCHEMBL26101805 | 0.80 | KIT (0.46) | KITEGFRKDRFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |