Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 13/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 3/20 | 0.41 |
| ▸ | RAF1 | P04049 | 6/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099737 | 0.92 | BRAF (0.46) | BRAFKITRAF1KDRAURKB | |
| SCHEMBL26101857 | 0.89 | KIT (0.42) | BRAFKITRAF1KDR | |
| SCHEMBL26103289 | 0.86 | KIT (0.43) | KITENPP1KDRAURKBIRAK4 | |
| SCHEMBL26103479 | 0.85 | EGFR (0.44) | PDE10AKITRAF1ENPP1KDR | |
| SCHEMBL26102560 | 0.84 | EGFR (0.48) | KITKDRAURKBIRAK4 | |
| SCHEMBL30394282 | 0.84 | KIT (0.43) | BRAFKITRAF1ENPP1KDR | |
| SCHEMBL26102835 | 0.84 | KIT (0.43) | BRAFKITRAF1ENPP1KDR | |
| SCHEMBL26101314 | 0.83 | KIT (0.42) | KITENPP1KDRAURKBIRAK4 | |
| SCHEMBL26102536 | 0.83 | MAPK7 (0.41) | PDE10AKITENPP1KDR | |
| SCHEMBL26101918 | 0.81 | MCHR1 (0.48) | KITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |