SCHEMBL26099300 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	KDR	P35968	10/20	0.44

▸	MAPK7	Q13164	1/20	0.42

▸	FLT1	P17948	5/20	0.40

▸	FLT4	P35916	5/20	0.40

▸	EGFR	P00533	5/20	0.40

▸	FGFR1	P11362	3/20	0.40

▸	ERBB2	P04626	2/20	0.40

▸	EPHA2	P29317	2/20	0.40

▸	EPHB4	P54760	2/20	0.40

▸	PDGFRB	P09619	1/20	0.39

▸	KIT	P10721	4/20	0.39

▸	HTR1A	P08908	1/20	0.39

▸	HTR7	P34969	1/20	0.39

▸	SLC2A1	P11166	1/20	0.39

▸	PDE10A	Q9Y233	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26101193	0.92	MAPK7 (0.43)	KDRMAPK7FLT1FLT4EGFR
SCHEMBL26100179	0.92	KIT (0.44)	KDRMAPK7FLT1FLT4EGFR
SCHEMBL26101421	0.92	MAPK7 (0.43)	KDRMAPK7FLT1FLT4EGFR
SCHEMBL26103463	0.88	MAPK7 (0.44)	KDRMAPK7FLT1EGFRERBB2
SCHEMBL30394062	0.87	EGFR (0.49)	KDRMAPK7FLT1FLT4EGFR
SCHEMBL26101933	0.87	EGFR (0.49)	KDRMAPK7FLT1FLT4EGFR
SCHEMBL26101018	0.86	EGFR (0.47)	KDRMAPK7FLT1FLT4EGFR
SCHEMBL30891778	0.86	MAPK7 (0.45)	KDRMAPK7FLT1FLT4EGFR
SCHEMBL26099862	0.86	MAPK7 (0.45)	KDRMAPK7FLT1FLT4EGFR
SCHEMBL26103289	0.86	KIT (0.43)	KDRFLT1FLT4EGFRFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023075529-A1	QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF	보로노이바이오 주식회사	2023-05-04	—	—	WO	claimed