Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.51 |
| ▸ | EGFR | P00533 | 12/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.51 |
| ▸ | FLT1 | P17948 | 9/20 | 0.51 |
| ▸ | FLT4 | P35916 | 9/20 | 0.51 |
| ▸ | KIT | P10721 | 5/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | TEK | Q02763 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.51 |
| ▸ | KIF5B | P33176 | 2/20 | 0.51 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | CIT | O14578 | 1/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.51 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | STK10 | O94804 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099433 | 0.88 | EGFR (0.52) | KDREGFRKITPDGFRBFLT3 | |
| SCHEMBL30394281 | 0.88 | EGFR (0.52) | KDREGFRKITPDGFRBFLT3 | |
| SCHEMBL26534393 | 0.85 | PDGFRB (0.46) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL26099032 | 0.82 | EGFR (0.51) | KDREGFRKITPDGFRBROCK2 | |
| SCHEMBL26103039 | 0.82 | EGFR (0.50) | KDREGFRKITPDGFRBCSF1R | |
| SCHEMBL26100864 | 0.81 | KIT (0.44) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL26099430 | 0.81 | KIT (0.48) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL26100883 | 0.80 | KIT (0.51) | KDREGFRFLT1FLT4KIT | |
| SCHEMBL26103035 | 0.80 | KIT (0.46) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL29238247 | 0.80 | KIT (0.50) | KDREGFRFGFR1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |