Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.39 |
| ▸ | KIT | P10721 | 5/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.36 |
| ▸ | FLT1 | P17948 | 3/20 | 0.36 |
| ▸ | FLT4 | P35916 | 3/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102003 | 0.93 | EGFR (0.39) | KDRKITEGFRFGFR1FLT1 | |
| SCHEMBL26103100 | 0.87 | PIK3CD (0.41) | KDRKITEGFRENPP1PDGFRB | |
| SCHEMBL26101555 | 0.83 | KIT (0.42) | KDRKITEGFRFGFR1FLT1 | |
| SCHEMBL26101193 | 0.80 | MAPK7 (0.43) | KDRKITEGFRFGFR1FLT1 | |
| SCHEMBL26101421 | 0.80 | MAPK7 (0.43) | KDRKITEGFRFGFR1FLT1 | |
| SCHEMBL26101865 | 0.80 | KDR (0.45) | KDRKITEGFRFGFR1FLT1 | |
| SCHEMBL26102638 | 0.78 | KDR (0.41) | KDRKITEGFRFGFR1FLT1 | |
| SCHEMBL26102187 | 0.77 | PIK3CD (0.41) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL26103463 | 0.76 | MAPK7 (0.44) | KDRKITEGFRFLT1ERBB2 | |
| SCHEMBL26101448 | 0.75 | KIT (0.44) | KDRKITEGFRFLT4ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |