SCHEMBL26101193 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK7	Q13164	1/20	0.43

▸	KDR	P35968	7/20	0.43

▸	CTSS	P25774	1/20	0.40

▸	EGFR	P00533	5/20	0.40

▸	FLT1	P17948	5/20	0.40

▸	FLT4	P35916	5/20	0.40

▸	KIT	P10721	4/20	0.40

▸	FGFR1	P11362	3/20	0.40

▸	HTR1A	P08908	1/20	0.40

▸	HTR7	P34969	1/20	0.40

▸	SLC2A1	P11166	1/20	0.40

▸	PDE10A	Q9Y233	1/20	0.40

▸	EPHA2	P29317	1/20	0.38

▸	EPHB4	P54760	1/20	0.38

▸	PDGFRB	P09619	1/20	0.38

▸	BTK	Q06187	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26101421	1.00	MAPK7 (0.43)	MAPK7KDRCTSSEGFRFLT1
SCHEMBL26103463	0.96	MAPK7 (0.44)	MAPK7KDREGFRFLT1KIT
SCHEMBL26102638	0.93	KDR (0.41)	MAPK7KDRCTSSEGFRFLT1
SCHEMBL26099300	0.92	KDR (0.44)	MAPK7KDREGFRFLT1FLT4
SCHEMBL30891778	0.92	MAPK7 (0.45)	MAPK7KDREGFRFLT1FLT4
SCHEMBL26099862	0.92	MAPK7 (0.45)	MAPK7KDREGFRFLT1FLT4
SCHEMBL26101933	0.88	EGFR (0.49)	MAPK7KDREGFRFLT1FLT4
SCHEMBL30394062	0.88	EGFR (0.49)	MAPK7KDREGFRFLT1FLT4
SCHEMBL26103141	0.87	EGFR (0.49)	MAPK7EGFRKITPDE10A
SCHEMBL26100162	0.86	MAPK7 (0.48)	MAPK7KDREGFRKITHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023075529-A1	QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF	보로노이바이오 주식회사	2023-05-04	—	—	WO	claimed