Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 8/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102003 | 0.92 | EGFR (0.39) | EGFRIRAK4EPHA2EPHB4KIT | |
| SCHEMBL26102187 | 0.90 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGACHE | |
| SCHEMBL26100989 | 0.87 | KDR (0.39) | EGFREPHA2EPHB4KITPDGFRB | |
| SCHEMBL26101324 | 0.82 | EGFR (0.44) | ACHEBACE1EGFRKITPDGFRB | |
| SCHEMBL26100162 | 0.80 | MAPK7 (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGACHE | |
| SCHEMBL26102536 | 0.77 | MAPK7 (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGACHE | |
| SCHEMBL26101800 | 0.75 | EGFR (0.52) | EGFRKITPDGFRAKDR | |
| SCHEMBL26101259 | 0.74 | EGFR (0.44) | EGFRKITPDGFRBPDGFRAFLT3 | |
| SCHEMBL28349038 | 0.74 | KDR (0.50) | PDGFRBPDGFRAFLT3KDR | |
| SCHEMBL29238245 | 0.73 | EGFR (0.44) | ACHEBACE1EGFRKITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |