Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | KIT | P10721 | 4/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | KIF5B | P33176 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102417 | 0.85 | KIT (0.46) | ENPP1EGFRKITPDK1AURKB | |
| SCHEMBL26101411 | 0.84 | ENPP1 (0.47) | ENPP1EGFRKITPDK1PDK2 | |
| SCHEMBL26101620 | 0.79 | KIT (0.46) | ENPP1EGFRKITPDK1AURKB | |
| SCHEMBL26101506 | 0.79 | KDR (0.53) | EGFRKITAURKBAURKARET | |
| SCHEMBL4725216 | 0.77 | EGFR (0.58) | EGFRKITAURKBAURKABRAF | |
| SCHEMBL30393934 | 0.77 | HSD17B2 (0.53) | ENPP1EGFRKITAURKBAURKA | |
| SCHEMBL26102475 | 0.77 | KDR (0.44) | ENPP1EGFRKITPDK1AURKB | |
| SCHEMBL22300110 | 0.77 | KIT (0.55) | ENPP1EGFRKITPDK1AURKA | |
| SCHEMBL4729758 | 0.76 | EGFR (0.48) | ENPP1EGFRKITPDK1AURKB | |
| SCHEMBL26101625 | 0.76 | KDR (0.65) | EGFRAURKBAURKAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |