Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 5/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 3/20 | 0.40 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KIF5B | P33176 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101616 | 0.84 | ENPP1 (0.45) | ENPP1EGFRKITPDK1PDK2 | |
| SCHEMBL26102256 | 0.81 | PDGFRB (0.51) | EGFRKITBRAFRAF1KDR | |
| SCHEMBL4727998 | 0.79 | EGFR (0.58) | EGFRKITBRAFRAF1RET | |
| SCHEMBL26098297 | 0.79 | EGFR (0.51) | ENPP1EGFRKITRAF1KDR | |
| SCHEMBL26100098 | 0.78 | EGFR (0.56) | EGFRKITHTTRETKIF5B | |
| SCHEMBL26101960 | 0.78 | KDR (0.54) | EGFRKITRETKIF5BKDR | |
| SCHEMBL26101620 | 0.76 | KIT (0.46) | ENPP1EGFRKITPDK1PDK2 | |
| SCHEMBL5569427 | 0.76 | KIT (0.58) | ENPP1EGFRKITKDR | |
| SCHEMBL22164766 | 0.75 | KIT (0.57) | ENPP1EGFRKITPDK1ALDH1A1 | |
| SCHEMBL30393934 | 0.74 | HSD17B2 (0.53) | ENPP1EGFRKITALDH1A1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |