Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | BRAF | P15056 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26098271 | 0.87 | EGFR (0.46) | KDRKITAURKBEGFRBRAF | |
| SCHEMBL26100901 | 0.81 | KDR (0.44) | KDRKITAURKBENPP1EGFR | |
| SCHEMBL26098922 | 0.80 | KDR (0.52) | KDRKITAURKBBRAFAURKA | |
| SCHEMBL26101061 | 0.78 | KDR (0.54) | KDRAURKBEGFRBRAFAURKA | |
| SCHEMBL26101616 | 0.77 | ENPP1 (0.45) | KDRKITAURKBENPP1EGFR | |
| SCHEMBL30891796 | 0.75 | KDR (0.50) | KDRAURKBEGFRBRAFAURKA | |
| SCHEMBL29238225 | 0.75 | KDR (0.50) | KDRAURKBEGFRBRAFAURKA | |
| SCHEMBL26101411 | 0.74 | ENPP1 (0.47) | KDRKITENPP1EGFRBRAF | |
| SCHEMBL26101620 | 0.72 | KIT (0.46) | KDRKITAURKBENPP1EGFR | |
| SCHEMBL26101028 | 0.71 | AURKB (0.47) | KDRKITAURKBEGFRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |