Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747578 | 0.87 | SMN1; SMN2 (0.59) | ALDH1A1HPGDSMN1; SMN2MAPTRAB9A | |
| SCHEMBL26099188 | 0.83 | SMN1; SMN2 (0.54) | ALDH1A1HPGDSMN1; SMN2FFAR1MAPT | |
| SCHEMBL26098711 | 0.82 | SMN1; SMN2 (0.66) | ALDH1A1HPGDSMN1; SMN2FFAR1MAPT | |
| SCHEMBL26102577 | 0.82 | RAB9A (0.54) | ALDH1A1FFAR1MAPTGAAHIF1A | |
| SCHEMBL26101450 | 0.81 | MAPT (0.50) | ALDH1A1HPGDSMN1; SMN2FFAR1MAPT | |
| SCHEMBL23747788 | 0.79 | SMN1; SMN2 (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTGAA | |
| SCHEMBL23747787 | 0.79 | SMN1; SMN2 (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTGAA | |
| SCHEMBL23747343 | 0.78 | SMN1; SMN2 (0.59) | ALDH1A1HPGDSMN1; SMN2MAPTRAB9A | |
| SCHEMBL26101541 | 0.78 | HRH3 (0.52) | ALDH1A1HPGDSMN1; SMN2FFAR1MAPT | |
| SCHEMBL26099623 | 0.77 | SMN1; SMN2 (0.58) | ALDH1A1HPGDSMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | ALDH1A1 2019/4885HPGD 355/4885SMN1; SMN2 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.