Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 6/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101625 | 0.85 | KDR (0.65) | KDRJAK2EGFR | |
| SCHEMBL26101516 | 0.80 | KDR (0.63) | KDREGFRPDGFRBFLT4 | |
| SCHEMBL26098635 | 0.80 | MET (0.46) | KDREGFRPDGFRAPDGFRBFLT3 | |
| SCHEMBL26102422 | 0.80 | KIT (0.47) | KDREGFRPDGFRAPDGFRBFLT3 | |
| SCHEMBL26102417 | 0.78 | KIT (0.46) | EGFRPDGFRAPDGFRB | |
| SCHEMBL30394508 | 0.73 | PDGFRB (0.54) | KDREGFRPDGFRACSF1RPDGFRB | |
| SCHEMBL26098752 | 0.73 | PDGFRB (0.54) | KDREGFRPDGFRACSF1RPDGFRB | |
| SCHEMBL30394637 | 0.73 | KDR (0.55) | KDREGFRCSF1RPDGFRBFLT4 | |
| SCHEMBL26535641 | 0.73 | KDR (0.55) | KDREGFRCSF1RPDGFRBFLT4 | |
| SCHEMBL30394611 | 0.72 | KDR (0.54) | KDREGFRPDGFRACSF1RPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |