Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104159 | 0.87 | SLC22A12 (0.35) | MAP2K1KDM5B | |
| SCHEMBL26101458 | 0.80 | EGLN2 (0.36) | EGLN2NAMPTKDM4EMAP2K1GAA | |
| SCHEMBL26101807 | 0.79 | NR1I2 (0.36) | ALDH1A1HCRTR1HCRTR2CYP1A2CYP3A4 | |
| SCHEMBL26099432 | 0.77 | NR1I2 (0.41) | EGLN2ALDH1A1HPGDCYP11B2CYP11B1 | |
| SCHEMBL26102005 | 0.75 | NR1I2 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL11520744 | 0.70 | CA12 (0.46) | EGLN2NAMPTKDM4EMAP2K1GAA | |
| SCHEMBL409948 | 0.67 | MEN1 (0.50) | MAP2K1GAAALDH1A1CYP11B2CYP11B1 | |
| SCHEMBL289565 | 0.67 | LRRK2 (0.45) | NAMPTKDM4EGAAALDH1A1HPGD | |
| SCHEMBL5961092 | 0.67 | CA12 (0.61) | NAMPTKDM4EGAAALDH1A1HPGD | |
| SCHEMBL16951317 | 0.67 | CA12 (0.40) | EGLN2NAMPTKDM4EMAP2K1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4423090-A2 | ANTAGONISTS OF GPR39 PROTEIN | Vasocardea, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023076219-A2 | ANTAGONISTS OF GPR39 PROTEIN | VASOCARDEA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |