Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 7/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099432 | 0.87 | NR1I2 (0.41) | NR1I2CACNA1BSMOFASNRORC | |
| SCHEMBL26101807 | 0.81 | NR1I2 (0.36) | NR1I2CACNA1BHCRTR1HCRTR2FASN | |
| SCHEMBL26099356 | 0.76 | NR1I2 (0.42) | NR1I2CACNA1BSMOHCRTR1HCRTR2 | |
| SCHEMBL30429790 | 0.76 | NR1I2 (0.42) | NR1I2CACNA1BSMOHCRTR1HCRTR2 | |
| SCHEMBL26104159 | 0.76 | SLC22A12 (0.35) | — | |
| SCHEMBL30430028 | 0.75 | MBTD1 (0.42) | NR1I2CACNA1BSMOHCRTR1HCRTR2 | |
| SCHEMBL26102446 | 0.75 | CFTR (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL26100540 | 0.75 | MBTD1 (0.42) | NR1I2CACNA1BSMOHCRTR1HCRTR2 | |
| SCHEMBL26105235 | 0.74 | NR1I2 (0.39) | NR1I2CACNA1BSMOFASNRBP4 | |
| SCHEMBL26102345 | 0.74 | FASN (0.38) | NR1I2CACNA1BSMOHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076219-A2 | ANTAGONISTS OF GPR39 PROTEIN | VASOCARDEA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |