Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.65 |
| ▸ | MAOA | P21397 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MDH2 | P40926 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956495 | 0.90 | MAOB (0.79) | MAOBMAOAALDH1A1HPGDMDH2 | |
| SCHEMBL26107786 | 0.89 | MAOB (0.56) | MAOBMAOAALDH1A1HPGDMDH2 | |
| SCHEMBL26105385 | 0.89 | MAOA (0.56) | MAOBMAOAALDH1A1HPGDMDH2 | |
| SCHEMBL26106454 | 0.89 | SLC16A3 (0.60) | MAOBMAOAALDH1A1HPGDMDH2 | |
| SCHEMBL26105868 | 0.89 | MAOB (0.64) | MAOBMAOAMEN1KMT2AACHE | |
| SCHEMBL26107440 | 0.89 | MAOB (0.64) | MAOBMAOAACHE | |
| SCHEMBL26105328 | 0.89 | MAOB (0.64) | MAOBMAOAALDH1A1HPGDMDH2 | |
| SCHEMBL17347205 | 0.84 | MAOB (0.61) | MAOBMAOAALDH1A1SLC16A3MAPT | |
| SCHEMBL24471022 | 0.83 | MAOB (0.66) | MAOBMAOAALDH1A1HPGDMDH2 | |
| SCHEMBL21591464 | 0.82 | MAOB (0.57) | MAOBMAOAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070780-A1 | MONOAMINE OXIDASE B INHIBITOR HAVING POTENTIAL IRON CHELATING ACTIVITY AND USE THEREOF | 浙江工业大学 | 2023-05-04 | — | — | WO | disclosed |
| CN-114149417-A | Monoamine oxidase B inhibitor with potential iron chelation activity and application thereof | 浙江工业大学 | 2022-03-08 | — | — | CN | disclosed |