Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | HPGD | P15428 | 8/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.51 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105762 | 0.89 | ALDH1A1 (0.75) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL30228225 | 0.87 | ALDH1A1 (0.73) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL20839119 | 0.87 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL30762949 | 0.87 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL30762890 | 0.87 | ALDH1A1 (0.66) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL20839443 | 0.87 | ALDH1A1 (0.66) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL21629541 | 0.83 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL21629540 | 0.83 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL30228298 | 0.81 | ALDH1A1 (0.77) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL20839059 | 0.81 | ALDH1A1 (0.77) | ALDH1A1HPGDKDM4ERECQLAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684762-B1 | COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2023-05-03 | — | — | EP | claimed |