Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105692 | 1.00 | HPGD (0.38) | HPGDKMT2ASMN1; SMN2HTR6KDM4E | |
| SCHEMBL26106259 | 1.00 | HPGD (0.38) | HPGDKMT2ASMN1; SMN2HTR6KDM4E | |
| SCHEMBL20503412 | 0.83 | KDM4E (0.39) | SMN1; SMN2KDM4EALDH1A1CHRM2HRH3 | |
| SCHEMBL17205682 | 0.79 | SMN1; SMN2 (0.39) | HPGDKMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17205680 | 0.79 | SMN1; SMN2 (0.39) | HPGDKMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17400448 | 0.79 | IRAK4 (0.39) | KMT2AKDM4EALDH1A1HRH3TSHR | |
| SCHEMBL1498362 | 0.77 | GABRA1 (0.39) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL3272691 | 0.77 | HRH3 (0.40) | KMT2AKDM4EALDH1A1CHRM2CHRM1 | |
| SCHEMBL986268 | 0.77 | HRH3 (0.43) | KDM4EALDH1A1HRH3 | |
| SCHEMBL26929406 | 0.74 | TPSAB1 (0.41) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072270-A1 | PROTAC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | 百极弘烨(南通)医药科技有限公司 | 2023-05-04 | — | — | WO | disclosed |