Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 8/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 5/20 | 0.32 |
| ▸ | HRH1 | P35367 | 4/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322548 | 0.84 | FFAR1 (0.46) | FFAR1GSK3BDYRK1AACHE | |
| SCHEMBL25810563 | 0.82 | FFAR1 (0.43) | FFAR1DGAT1USP30GSK3BDYRK1A | |
| SCHEMBL320321 | 0.81 | FFAR1 (0.42) | FFAR1USP30DDB1CRBNACHE | |
| SCHEMBL21626900 | 0.81 | FFAR1 (0.44) | FFAR1GSK3BDYRK1A | |
| SCHEMBL25810566 | 0.80 | FFAR1 (0.42) | FFAR1DGAT1USP30GSK3BDYRK1A | |
| SCHEMBL658691 | 0.79 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL28254657 | 0.79 | FFAR1 (0.44) | FFAR1DGAT1USP30DDB1CRBN | |
| SCHEMBL2515083 | 0.79 | FFAR1 (0.47) | FFAR1DGAT1USP30 | |
| SCHEMBL28649940 | 0.78 | FFAR1 (0.46) | FFAR1USP30ACHE | |
| SCHEMBL25810466 | 0.78 | FFAR1 (0.42) | FFAR1DGAT1USP30GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072301-A1 | PYRAZOLO[3,4-D]PYRIMIDIN-3-ONE COMPOUND AND MEDICAL USE THEREOF | 正大天晴药业集团股份有限公司 | 2023-05-04 | — | — | WO | disclosed |