Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440180 | 0.81 | TRPC6 (0.56) | ALDH1A1CYP1A2MAPTHPGDCYP2C19 | |
| SCHEMBL21045812 | 0.81 | TRPC6 (0.56) | ALDH1A1CYP1A2MAPTHPGDCYP2C19 | |
| SCHEMBL14659263 | 0.78 | MEN1 (0.48) | KDM4EGABRPGABRDPDE5AALDH1A1 | |
| SCHEMBL21045835 | 0.75 | TRPC6 (0.55) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL30439720 | 0.75 | TRPC6 (0.55) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL5806655 | 0.75 | TRPC6 (0.53) | KDM4ELMNACYP1A2CYP3A4MAPT | |
| SCHEMBL21633979 | 0.74 | EPAS1 (0.43) | MAPTPKMMAPK1 | |
| SCHEMBL21274211 | 0.73 | SLC6A4 (0.48) | ALDH1A1HPGDHIF1ANPC1SMN1; SMN2 | |
| SCHEMBL30803664 | 0.73 | SLC6A4 (0.48) | ALDH1A1HPGDHIF1ANPC1SMN1; SMN2 | |
| SCHEMBL21045659 | 0.73 | TRPC6 (0.48) | KDM4EGABRPGABRDPDE5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49699-E1 | Inhibitors of TRPC6 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-17 | — | — | US | disclosed |