Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612161 | 1.00 | ALPL (0.40) | ALPLHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL20552092 | 0.74 | ALPL (0.39) | ALPLHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL15995723 | 0.71 | TP53 (0.42) | ALPLHTTKMT2AALDH1A1MAPK1 | |
| SCHEMBL30881780 | 0.71 | TP53 (0.42) | ALPLHTTKMT2AALDH1A1MAPK1 | |
| SCHEMBL30611994 | 0.70 | ALDH1A1 (0.33) | HTTKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL26106122 | 0.70 | ALDH1A1 (0.33) | HTTKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL30367456 | 0.69 | ALPL (0.40) | ALPLKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL30612152 | 0.68 | ALDH1A1 (0.32) | HTTKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL26107180 | 0.68 | ALDH1A1 (0.32) | HTTKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL25239396 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499629-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183919-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |