Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 13/20 | 0.49 |
| ▸ | SRC | P12931 | 7/20 | 0.49 |
| ▸ | TEK | Q02763 | 12/20 | 0.46 |
| ▸ | KDR | P35968 | 11/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | ABL2 | P42684 | 2/20 | 0.43 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659188 | 1.00 | LCK (0.49) | LCKSRCTEKKDREGFR | |
| SCHEMBL26587238 | 0.94 | LCK (0.49) | LCKSRCTEKKDREGFR | |
| SCHEMBL26109125 | 0.86 | LCK (0.44) | LCKSRCTEKKDREGFR | |
| SCHEMBL30582591 | 0.84 | LCK (0.42) | LCKSRCTEKKDREGFR | |
| SCHEMBL26108281 | 0.84 | LCK (0.42) | LCKSRCTEKKDREGFR | |
| SCHEMBL30303782 | 0.80 | LCK (0.47) | LCKSRCTEKKDRHCK | |
| SCHEMBL28693886 | 0.80 | LCK (0.47) | LCKTEKKDREGFRBTK | |
| SCHEMBL22676631 | 0.78 | BTK (0.53) | LCKSRCKDREGFRABL1 | |
| SCHEMBL31219400 | 0.78 | LCK (0.42) | LCKSRCTEKKDREGFR | |
| SCHEMBL22676199 | 0.77 | BTK (0.53) | LCKSRCKDREGFRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874707-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114126620-B | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |
| EP-3968999-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2022-03-23 | — | — | EP | disclosed |
| CN-114126620-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2022-03-01 | — | — | CN | disclosed |