Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612214 | 1.00 | HDAC6 (0.31) | HDAC6HDAC4HDAC1PDCD1LG2CD274 | |
| SCHEMBL26105455 | 0.80 | HRH4 (0.31) | HDAC6PDCD1LG2CD274HSP90AA1 | |
| SCHEMBL30612157 | 0.80 | HRH4 (0.31) | HDAC6PDCD1LG2CD274HSP90AA1 | |
| SCHEMBL31347139 | 0.80 | KMT2A (0.33) | HDAC6HDAC4HDAC1 | |
| SCHEMBL26104758 | 0.80 | KMT2A (0.33) | HDAC6HDAC4HDAC1 | |
| SCHEMBL30612045 | 0.79 | KDM4E (0.46) | HDAC6HDAC4HDAC1PDCD1LG2CD274 | |
| SCHEMBL26108500 | 0.79 | KDM4E (0.46) | HDAC6HDAC4HDAC1PDCD1LG2CD274 | |
| SCHEMBL30612138 | 0.77 | NOTUM (0.32) | — | |
| SCHEMBL26105306 | 0.77 | NOTUM (0.32) | — | |
| SCHEMBL31347050 | 0.76 | TLR7 (0.39) | HDAC6HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499629-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183919-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |