Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108500 | 1.00 | KDM4E (0.46) | KDM4EADCY10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30611894 | 0.83 | KDM4E (0.52) | KDM4EADCY10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26107710 | 0.83 | KDM4E (0.52) | KDM4EADCY10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26105230 | 0.80 | KDM4E (0.49) | KDM4EADCY10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31347186 | 0.80 | KDM4E (0.49) | KDM4EADCY10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31347137 | 0.79 | KDM4E (0.48) | KDM4EADCY10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31347211 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1MAPTPLA2G2APOLB | |
| SCHEMBL30611844 | 0.79 | KDM4E (0.48) | KDM4EADCY10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30612114 | 0.79 | KDM4E (0.48) | KDM4EADCY10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26105877 | 0.79 | KDM4E (0.48) | KDM4EADCY10ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |
| EP-4499629-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183919-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |