Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105455 | 1.00 | HRH4 (0.31) | HRH4PDCD1LG2CD274HDAC6HSP90AA1 | |
| SCHEMBL30611846 | 0.81 | CYP19A1 (0.32) | HDAC6HSP90AA1 | |
| SCHEMBL26105147 | 0.81 | CYP19A1 (0.32) | HDAC6HSP90AA1 | |
| SCHEMBL30612169 | 0.81 | GLO1 (0.35) | HSP90AA1 | |
| SCHEMBL26107263 | 0.81 | GLO1 (0.35) | HSP90AA1 | |
| SCHEMBL30612214 | 0.80 | HDAC6 (0.31) | PDCD1LG2CD274HDAC6HSP90AA1 | |
| SCHEMBL26108562 | 0.80 | HDAC6 (0.31) | PDCD1LG2CD274HDAC6HSP90AA1 | |
| SCHEMBL31347169 | 0.78 | SLC2A1 (0.37) | HDAC6 | |
| SCHEMBL26105860 | 0.78 | SLC2A1 (0.37) | HDAC6 | |
| SCHEMBL30611847 | 0.77 | CYP2A6 (0.36) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |
| EP-4499629-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183919-A1 | BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS | ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |