Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108781 | 0.91 | BTK (0.35) | RIPK2PTPN11EGFRLRRK2FGFR1 | |
| SCHEMBL26109317 | 0.89 | SRC (0.41) | EGFRSRCPIK3CD | |
| SCHEMBL26109178 | 0.89 | FGFR1 (0.31) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL26107955 | 0.87 | RET (0.37) | EGFRLRRK2SRCPIK3CDEIF2AK3 | |
| SCHEMBL26107398 | 0.86 | — | — | |
| SCHEMBL26109353 | 0.86 | RET (0.32) | EGFRLRRK2SRCPIK3CD | |
| SCHEMBL26109533 | 0.85 | KIT (0.35) | FGFR1FGFR2FGFR4FGFR3PIK3CD | |
| SCHEMBL26105475 | 0.85 | LRRK2 (0.32) | LRRK2 | |
| SCHEMBL30582620 | 0.84 | RIPK2 (0.40) | RIPK2PTPN11EGFRLRRK2MAP4K4 | |
| SCHEMBL26109630 | 0.84 | RIPK2 (0.40) | RIPK2PTPN11EGFRLRRK2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | claimed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |