Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | FGR | P09769 | 1/20 | 0.35 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.35 |
| ▸ | TXK | P42681 | 1/20 | 0.35 |
| ▸ | FRK | P42685 | 1/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26109630 | 1.00 | RIPK2 (0.40) | RIPK2CCNT1CDK9LRRK2FGR | |
| SCHEMBL30582605 | 0.89 | CCNT1 (0.38) | RIPK2CCNT1CDK9LRRK2PIK3CD | |
| SCHEMBL26106044 | 0.89 | CCNT1 (0.38) | RIPK2CCNT1CDK9LRRK2PIK3CD | |
| SCHEMBL30582584 | 0.88 | SRC (0.47) | PIK3CDPI4KBEGFRSRCABL1 | |
| SCHEMBL26109072 | 0.88 | SRC (0.47) | PIK3CDPI4KBEGFRSRCABL1 | |
| SCHEMBL30582633 | 0.88 | CCNT1 (0.34) | CCNT1CDK9LRRK2FGREPHA1 | |
| SCHEMBL26106109 | 0.88 | CCNT1 (0.34) | CCNT1CDK9LRRK2FGREPHA1 | |
| SCHEMBL30582601 | 0.85 | PIK3CD (0.40) | CCNT1CDK9LRRK2FGREPHA1 | |
| SCHEMBL26105782 | 0.85 | PIK3CD (0.40) | CCNT1CDK9LRRK2FGREPHA1 | |
| SCHEMBL26109006 | 0.84 | RIPK2 (0.35) | RIPK2LRRK2PIK3CDRIPK1EIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |