Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TRIP13 | Q15645 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26083602 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ATMTRIP13MEN1KMT2A | |
| SCHEMBL26109454 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ATMTRIP13MEN1KMT2A | |
| SCHEMBL3187253 | 0.84 | ATM (0.58) | ALDH1A1ATMTRIP13MEN1KMT2A | |
| SCHEMBL3187244 | 0.84 | ATM (0.58) | ALDH1A1ATMTRIP13MEN1KMT2A | |
| SCHEMBL3186419 | 0.83 | ALDH1A1 (0.62) | ALDH1A1ATMTRIP13MEN1KMT2A | |
| SCHEMBL3186430 | 0.83 | ALDH1A1 (0.62) | ALDH1A1ATMTRIP13MEN1KMT2A | |
| SCHEMBL3196397 | 0.81 | USP2 (0.51) | ALDH1A1MAPT | |
| SCHEMBL3196409 | 0.81 | USP2 (0.51) | ALDH1A1MAPT | |
| SCHEMBL3198129 | 0.78 | POLB (0.54) | ALDH1A1ATMMEN1KMT2A | |
| SCHEMBL3198137 | 0.78 | POLB (0.54) | ALDH1A1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034091-A1 | Small molecule inhibitors of lanosterol synthase | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-01-30 | — | — | US | disclosed |
| WO-2023192782-A2 | SMALL MOLECULE INHIBITORS OF LANOSTEROL SYNTHASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034091-A1 | Small molecule inhibitors of lanosterol synthase | LSS, CYP51A1, CYP27A1 | ALDH1A1 3791/4885ATM 3875/4885TRIP13 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.