Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 6/20 | 0.43 |
| ▸ | BTK | Q06187 | 13/20 | 0.40 |
| ▸ | BLK | P51451 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TEC | P42680 | 1/20 | 0.39 |
| ▸ | TXK | P42681 | 1/20 | 0.39 |
| ▸ | BMX | P51813 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ABL2 | P42684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26109362 | 0.91 | BTK (0.48) | RIPK2BTKBLKEGFRERBB2 | |
| SCHEMBL30582530 | 0.91 | BTK (0.48) | RIPK2BTKBLKEGFRERBB2 | |
| SCHEMBL26107236 | 0.90 | BTK (0.43) | BTKBLKEGFRERBB2RET | |
| SCHEMBL30582631 | 0.90 | PDE2A (0.43) | RIPK2BTKEGFRRETABL1 | |
| SCHEMBL30582623 | 0.87 | RIPK2 (0.45) | RIPK2EGFRABL1SRCABL2 | |
| SCHEMBL26108141 | 0.87 | RIPK2 (0.45) | RIPK2EGFRABL1SRCABL2 | |
| SCHEMBL26108026 | 0.82 | SRC (0.44) | RIPK2EGFRABL1SRCABL2 | |
| SCHEMBL30582544 | 0.82 | SRC (0.44) | RIPK2EGFRABL1SRCABL2 | |
| SCHEMBL30582519 | 0.82 | BTK (0.50) | BTKBLKEGFRERBB2RET | |
| SCHEMBL26105731 | 0.82 | BTK (0.50) | BTKBLKEGFRERBB2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091370-A1 | 5,6-FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |